The Mouse Anti-PTHR / PTHR1 Antibody from MyBioSource.com is a Mouse Monoclonal antibody to PTH1R. This antibody recognizes Human, Bovine, Canine, Horse, Non-Human Primate, and Porcine antigen. The Mouse Anti-PTHR / PTHR1 Antibody has been validated for the following applications: Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
PTHR1, a Parathyroid Hormone Receptor, mediates PTH-dependent regulation of mineral-ion homeostasis. It also mediates the paracrine action of PTHRP in endochondral bone formation. Mutations in this receptor are responsible for disorders of calcium and bone metabolism such as chondrodysplasia, hypercalcemia, and chronic renal failure. Three promoters, P1, P2, and P3, regulate the expression of PTHR